{"id":653,"date":"2009-08-20T00:00:00","date_gmt":"2009-08-20T00:00:00","guid":{"rendered":"http:\/\/www.innovationanthology.com\/import\/2018\/02\/01\/innovation-anthology-251\/"},"modified":"2018-02-25T21:30:08","modified_gmt":"2018-02-25T21:30:08","slug":"innovation-anthology-251","status":"publish","type":"post","link":"https:\/\/www.innovationanthology.com\/import\/2009\/08\/20\/innovation-anthology-251\/","title":{"rendered":"Innovation Anthology #251:"},"content":{"rendered":"<p><a href=\"http:\/\/innovationanthology.com\/uploads\/Innovation Anthology 251.mp3\">Download MP3 Link<\/a><\/p>\n<p>\nPrion research started by looking for the cause of mad cow disease.\n<\/p>\n<p>\nBut now scientists have discovered <b>misfolded prions<\/b> are linked to many other conditions, including <b>Alzheimer\u2019s disease <\/b>in humans.\n<\/p>\n<p><b><br \/>\nDr. Jean Phillipe Deslys<\/b> from the <b>Atomic Energy Commission<\/b> in France gives this insight into prion research using transgenic mice.\n<\/p>\n<p>\n<br \/>\nDR. JEAN PHILLIPE DESLYS:<\/b><em>  So it turns out that the  prion protein would be the intermediate necessary for the toxicity of these Alzheimer\u2019s oligomers.  Moreover when you look at  transgenic mice which do not express these prion protein, they are insensitive to the toxicity of these Alzheimer oligomers. And for the  normal animals which do express the prion protein and which are sensitive to the toxicity of these Alzheimer\u2019s oligomers, when you treat them with antibodies against the prion proteins, you protect them from the toxicity of the<br \/>\nAlzehimer\u2019s aggregates.  <\/em>\n<\/p>\n<p>\nDr. Jean Phillipe Deslys spoke in Edmonton at the recent Prion Conference.\n<\/p>\n<p><em><br \/>\nThanks today to the <b>Canadian Institutes for Health Research<\/em>\n<\/p>\n<p>\nFOR INNOVATION ANTHOLOGY<br \/>\nI&#8217;M CHERYL CROUCHER   <\/b>\n<\/p>\n<h2>Guest<\/h2>\n<h3> , <\/h3>\n<h4>, , , , <\/h4>\n<h2>Sponsor<\/h2>\n<h3><a href=\"http:\/\/www.cihr-irsc.gc.ca\">Canadian Institutes of Health Research<\/a><\/h3>\n<p><img decoding=\"async\" src=\"http:\/\/innovationanthology.com\/uploads\/cihr.jpg\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Program Date:<\/strong>\u00a02009-08-20<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prion research started by looking for the cause of mad cow disease.     But now scientists have discovered <b>misfolded prions<\/b> are linked to many other conditions, including <b>Alzheimer\u2019s disease<\/b> in humans.  <b>Dr. Jean Phillipe Deslys<\/b> from the Atomic Energy Commission in France gives this insight into prion research using transgenic mice.<\/p>\n","protected":false},"author":1,"featured_media":654,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,62,7,2],"tags":[],"class_list":["post-653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biotechnology","category-canadian-institutes-of-health-research","category-genomics","category-health-and-medicine","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"jetpack_featured_media_url":"https:\/\/www.innovationanthology.com\/import\/wp-content\/uploads\/2018\/02\/3-250jean_phillipe_deslyse.jpg","_links":{"self":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/comments?post=653"}],"version-history":[{"count":3,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/653\/revisions"}],"predecessor-version":[{"id":4569,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/653\/revisions\/4569"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/media\/654"}],"wp:attachment":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/media?parent=653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/categories?post=653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/tags?post=653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}