{"id":584,"date":"2009-05-26T00:00:00","date_gmt":"2009-05-26T00:00:00","guid":{"rendered":"http:\/\/www.innovationanthology.com\/import\/2018\/02\/01\/innovation-anthology-228\/"},"modified":"2018-02-25T21:30:05","modified_gmt":"2018-02-25T21:30:05","slug":"innovation-anthology-228","status":"publish","type":"post","link":"https:\/\/www.innovationanthology.com\/import\/2009\/05\/26\/innovation-anthology-228\/","title":{"rendered":"Innovation Anthology #228:"},"content":{"rendered":"<p><a href=\"http:\/\/innovationanthology.com\/uploads\/Innovation Anthology 228.mp3\">Download MP3 Link<\/a><\/p>\n<p> Misfolded prions are the culprits behind a number of neuro-degenerative diseases such as mad cow and chronic wasting disease. <\/p>\n<p> Genetic material called<strong> micro RNA&rsquo;s <\/strong>may play a role in determining whether prion proteins are normal or misfold leading to disease.   <\/p>\n<p><strong> Amrit Singh<\/strong> of the University of Manitoba is researching ways to deliver these micro RNA&rsquo;s to the brain.   She presented her findings at the poster competition at the  recent Prion Conference in Edmonton. <\/p>\n<p><strong> AMRIT SINGH:  <\/strong><em>During prion infection there is actually changes in micro RNA expression levels starting early in infection at 70 days.  Whereas the actual prion infection can&rsquo;t be detected until after death.  So we are hoping that using a micro RNA therapy can  help prolong the life of these animals   And there is a recent study using a rabies virus glycoprotein which you can inject into blood circulation   And it traverses the blood brain barrier directly.  So you just inject in the blood and it targets the brain. <\/em> <\/p>\n<p> If successful this research could lead to a treatment for prion diseases and remove the need to work directly with infectious prions   <\/p>\n<p><em> Thanks today to <strong>The Canadian Institutes for Health Research.<\/strong><\/em> <\/p>\n<p> <strong>FOR INNOVATION ANTHOLOGY, I&#8217;M CHERYL CROUCHER<\/strong> <\/p>\n<h2>Guest<\/h2>\n<h3> , <\/h3>\n<h4>, , , , <\/h4>\n<h2>Sponsor<\/h2>\n<h3><a href=\"http:\/\/www.cihr-irsc.gc.ca\">Canadian Institutes of Health Research<\/a><\/h3>\n<p><img decoding=\"async\" src=\"http:\/\/innovationanthology.com\/uploads\/cihr.jpg\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Program Date:<\/strong>\u00a02009-05-26<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Genetic material called <strong>micro RNA&rsquo;s<\/strong> may play a role in determining whether prion proteins are normal or misfold,  leading to disease.    <strong>Amrit Singh<\/strong> of the University of Manitoba is researching ways to deliver these micro RNA&rsquo;s to the brain.   She presented her findings at the poster competition at the  recent Prion Conference in Edmonton. <em>(Canadian Institutes for Health Research)<\/em><\/p>\n","protected":false},"author":1,"featured_media":585,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,62,2,26],"tags":[],"class_list":["post-584","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-agriculture","category-canadian-institutes-of-health-research","category-health-and-medicine","category-prions","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"jetpack_featured_media_url":"https:\/\/www.innovationanthology.com\/import\/wp-content\/uploads\/2018\/02\/228amrit_singh.jpg","_links":{"self":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/comments?post=584"}],"version-history":[{"count":3,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/584\/revisions"}],"predecessor-version":[{"id":4546,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/posts\/584\/revisions\/4546"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/media\/585"}],"wp:attachment":[{"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/media?parent=584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/categories?post=584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.innovationanthology.com\/import\/wp-json\/wp\/v2\/tags?post=584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}